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. 2016 Apr 30;22:446–453.

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Copyright © 2016 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Suppression of PGS activity in CEPI cells by steroids. A: Effect of 2-OHE2 on cellular viability. The horizontal axis shows the concentration of 2-OHE2 added to the medium, and the vertical axis shows the cellular viability in CEPI cells. B: The PGS activity of the cellular extract of CEPI cells with or without 10 μM steroids. NT, E2, or T means without a steroid, estradiol, or testosterone addition. The vertical axis shows the PGS activity ratio. The results are expressed as mean ± SD. Dunnett’s test was used to determine the significance of differences. * indicates a significant difference from the result in NT, p<0.05.