Figure 3.
PET/CT volume-rendered composite images of [18F]DCFPyL in a mouse bearing PSMA+ PC3 PIP and PSMA− PC3 flu tumors at (A) 0–30 minutes; (B) 30–60 minutes and (C) 3–3.5 hours post-injection. By 30 minutes radiochemical uptake was evident within the PSMA+ PC3 PIP tumor and kidneys. Radioactivity receded from kidneys faster than from tumor, and was not evident within kidneys by 3.5 hours post-injection. Radioactivity within bladder was due to excretion. At no time was radioactivity clearly visualized within the isogenic, PSMA-PC3 flu tumor. Adapted from Chen Y et al.]54