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. 2016 Apr 18;5(4):e002544. doi: 10.1161/JAHA.115.002544

Table 3.

SNPs Associated With Macrovascular/Epicardial Endothelial Dysfunction Significant Only Among Males

Chr. Significant SNP in Males Position Gene Region Risk Allele X/Y Overall Allele X Frequency OR Overall P Value Overall OR Men P Value Men OR Women P Value Women P Value SNP×Sex
1 rs17511046a 201376668a ADORA1 a G/A 0.93 1.17 0.5066 3.88 0.0068a 0.68 0.1609 0.0034a
4 rs3774933a 103645369a NFKB1 a G/A 0.39 1.06 0.6362 1.72 0.0085a 0.80 0.1472 0.0068a
4 rs1599961a 103662599a NFKB1 a A/G 0.39 1.06 0.6362 1.72 0.0085a 0.80 0.1472 0.0068a
6 rs20456 39432901 LOC100124373/KIF6 C/T 0.43 1.31 0.0283 1.70 0.0069a 1.10 0.5601 0.0622
6 k6_39474093 39474093 KIF6 T/A 0.06 1.95 0.0060 4.00 0.0047a 1.44 0.2188 0.0582

OR indicates, odds ratio; SNPs, single‐nucleotide polymorphisms.

a

SNPs both significant in sex and SNP×Sex.

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