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. Author manuscript; available in PMC: 2016 May 6.
Published in final edited form as: Pharmacol Biochem Behav. 2015 Oct 28;140:27–32. doi: 10.1016/j.pbb.2015.10.014

Fig. 3.

Fig. 3

The effect of 0.3 mg/kg oxytocin on ethanol gel or plain gel operant self-administration. Rats were injected I.P. with either oxytocin (indicated by arrow) or saline (all other days) 30 min prior to the start of the operant sessions. Separate groups of rats responded for either ethanol gel (n = 6) or plain gel (n = 6) reinforcement during the 30-min sessions. Panel A shows the consumption of plain gel and ethanol gel in grams of gel per kg body weight. Since the ethanol gel contained 10% ethanol (w/w) the baseline ethanol intake on saline injection days was about 1.2 g/kg ethanol/kg body wt (12 g gel/kg body wt). Panel B shows the consumption of plain and ethanol gel in calories consumed per kg body weight. Oxytocin significantly decreased ethanol consumption to a greater extent than plain gel consumption compared to saline injections both when graphed as grams of gel or calories. Shown are means ± SEM. * indicates p < 0.05 compared to same day ethanol gel consumption after saline injection.