Skip to main content
. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Neuroimage. 2015 Sep 12;124(Pt A):663–671. doi: 10.1016/j.neuroimage.2015.09.016

Table 3.

Statistical modeling of hemodynamic response function characteristics estimated with a fixed neuronal activity functiona.

HRFs Model fit
Model comparison
ACE
ADE
CE
AE
E
ACE vs. AE
ACE vs. CE
ADE vs. AE
ADE vs. E
AE vs. E
−2LL AIC −2LL AIC −2LL AIC −2LL AIC −2LL AIC Δχ2 P Δχ2 P Δχ2 P Δχ2 P Δχ2 P
L-MFG-H 761.49 −158.51 761.10 −158.90 765.50 −156.50 761.49 −160.51 777.42 −146.58 0.00 1 4.00 0.04 0.39 0.53 16.32 2.85E–04 15.93 6.57E–05
L-SMG-H 403.03 −264.97 402.96 −265.04 404.54 −265.46 403.03 −266.97 410.75 −261.25 0.00 1 1.51 0.22 0.08 0.78 7.79 0.02 7.72 5.47E–03
L-AG-H 723.84 −54.15 723.45 −54.55 726.22 −53.78 723.84 −56.15 732.57 −49.43 0.00 1 2.37 0.12 0.39 0.53 9.12 0.01 8.72 3.14E–03
R-MFG-H 713.04 −238.96 709.69 −242.31 718.71 −235.29 713.03 −240.96 724.26 −231.74 0.00 1 5.67 0.02 3.34 0.07 14.57 6.87E–04 11.22 8.07E–04
R-SMG-H 461.48 −316.52 460.44 −317.56 464.88 −315.12 461.48 −318.52 472.30 −309.70 0.00 1 3.40 0.06 1.04 0.31 11.86 2.66E–03 10.82 1.00E–03
R-AG-H 505.15 −330.85 502.03 −333.97 511.60 −326.40 505.15 −332.85 518.96 −321.04 0.00 1 6.45 0.01 3.12 0.08 16.93 2.11E–04 13.81 2.02E–04
L-MFG-T 1403.89 483.89 1403.88 483.88 1406.17 484.17 1403.89 482.89 1419.67 495.67 0.00 1 2.28 0.13 4.59E–03 0.95 15.79 3.72E–04 15.79 7.09E–05
L-SMG-T 1112.68 444.68 1111.78 443.78 1115.63 445.63 1112.68 442.68 1120.93 448.93 0.00 1 2.95 0.09 0.90 0.34 9.16 0.01 8.25 4.06E–03
L-AG-T 1301.32 523.32 1300.31 522.33 1303.92 523.92 1301.32 521.32 1308.25 526.25 0.00 1 2.60 0.11 0.99 0.32 7.92 0.02 6.93 8.48E–03
R-MFG-T 1536.88 584.88 1535.30 583.30 1540.72 586.72 1538.88 582.88 1546.94 590.94 0.00 1 3.84 0.05 1.58 0.21 11.64 2.97E–03 10.06 1.51E–03
R-SMG-T 1412.07 634.07 1411.49 633.49 1416.13 636.13 1412.07 632.07 1424.33 642.33 0.00 1 4.07 0.04 0.57 0.45 12.84 1.63E–03 12.26 4.61E–04
R-AG-T 1504.21 668.21 1500.99 664.99 1507.44 669.44 1504.21 666.21 1509.69 669.69 0.00 1 3.23 0.07 3.22 0.07 8.71 0.01 5.481 1.91E–02
L-MFG-W 1382.74 462.74 1382.34 462.34 1383.51 461.51 1382.74 460.74 1384.63 460.63 0.00 1 0.78 0.38 0.40 0.53 2.29 0.32 1.89 0.17
L-SMG-W 1016.31 348.31 1014.22 346.22 1018.43 348.43 1016.31 346.31 1019.53 347.53 0.00 1 2.12 0.15 2.09 0.15 5.31 0.07 3.21 0.07
L-AG-W 1217.83 439.83 1215.59 437.59 1222.61 442.61 1217.83 437.83 1228.94 446.94 0.00 1 4.77 0.03 2.24 0.13 13.35 1.25E–03 11.11 8.58E–04
R-MFG-W 1587.08 635.08 1587.06 635.06 1588.76 634.76 1587.08 633.08 1597.72 641.72 0.00 1 1.68 0.19 0.03 0.87 10.66 4.83E–03 10.64 1.11E–03
R-SMG-W 1405.65 627.65 1405.58 627.58 1406.21 626.21 1405.65 625.65 1408.14 626.14 0.00 1 0.56 0.45 0.07 0.79 2.56 0.28 2.49 0.02
R-AG-W 1520.72 684.72 1517.82 681.82 1522.93 684.93 1520.72 682.72 1524.17 684.17 0.00 1 2.21 0.14 2.90 0.09 6.35 0.04 3.45 0.06

Note that the P values are conservative with the assumption of standard chi-square distribution. Given a null distribution of parameterized variance component being a 50/50% mixture of a χ2(0) and χ2(1) (Dominicus et al., 2006), the P values should be half of the values reported in this table.

a

HRFs are hemodynamic response function characteristics estimated with a fixed neuronal activity function. L-: left; R-: right; MFG: middle frontal gyrus; SMG: supramarginal gyrus; AG: angular gyrus; H: height; T: time to peak; W: full width at half maximum of the HRF; A: additive genetic factors; C: common environmental factors; D: dominance genetic factors; E: unique environmental factors (E); −2LL: minus 2 × log-likelihood; AIC: Akaike Information Criterion; Δχ2: change in chi-square; P: unadjusted P values; aEb: a × 10b.