Table 3.
Summary of QUADAS‐2 Assessment of Selected Studies
| Study (Reference) | Risk of Bias | Applicability Concerns | |||||
|---|---|---|---|---|---|---|---|
| Patient Selection | Index Test | Reference Standard | Flow and Timing | Patient Selection | Index Test | Reference Standard | |
| Nagueh et al (1997)13 | Unclear | Low | Low | Low | Low | Low | Low |
| Nagueh et al (1998)14 | Low | Low | Low | Low | High | Low | Low |
| Ommen et al (2000)15 | Low | Low | Low | Low | Low | Low | Low |
| Gonzalez‐Vilchez et al (2002)16 | High | Low | Low | Low | High | Low | Low |
| Poerner et al (2003)17 | Low | Low | Low | Low | Low | High | Low |
| Rivas‐Gotz et al (2003)18 | Low | Low | Low | Low | Unclear | Unclear | Low |
| Dokanish et al (2004)19 | Unclear | Low | Low | Low | High | Unclear | Low |
| Mansencal et al (2004)20 | Low | Low | Low | Low | High | Unclear | Unclear |
| Arques et al (2005)21 | High | Low | High | High | High | Low | Low |
| Bruch et al (2005)22 | Unclear | Unclear | Unclear | Low | High | Low | Low |
| Hadano et al (2005)23 | Unclear | Unclear | Low | Low | Low | Unclear | Low |
| Kidawa et al (2005)24 | Low | Low | Low | Low | Low | Unclear | Low |
| Weber et al (2006)25 | Low | Low | Unclear | Unclear | High | Unclear | Low |
| Kasner et al (2007)26 | High | Low | Low | Low | High | Low | Low |
| Min et al (2007)27 | Low | Low | Low | Low | Low | Unclear | Low |
| Poerner et al (2007)28 | Low | Low | Low | Low | Low | High | Low |
| Wang et al (2007)29 | Unclear | Low | Low | Low | Unclear | Low | Low |
| Dokanish et al (2008)30 | Low | Low | Low | Low | Unclear | Unclear | Low |
| Ng et al (2008)31 | Unclear | Low | High | Low | Unclear | Low | Low |
| Rudko et al (2008)32 | Low | Low | Low | Low | High | Unclear | Low |
| Dini et al (2010)33 | Unclear | Low | Unclear | Low | Low | Unclear | Low |
| Dokanish et al (2010)34 | Low | Low | Unclear | Low | Unclear | Unclear | Low |
| Dokanish et al (2010)35 | Low | Low | Unclear | Low | Unclear | Unclear | Low |
| Jaubert et al (2010)36 | Low | Low | Low | Low | Low | Low | Low |
| Kasner et al (2010)37 | High | Low | Low | Low | High | Unclear | Low |
| Penicka et al (2010)38 | High | Unclear | Unclear | Low | Unclear | Unclear | Low |
| Bhella et al (2011)39 | High | Low | Low | Low | High | Unclear | Low |
| Hsiao et al (2011)40 | Unclear | Low | Low | Low | High | Low | Low |
| Kasner et al (2011)41 | Unclear | Low | Low | Low | Unclear | Low | Low |
| Maeder et al (2011)42 | Low | Low | Low | Low | Low | Unclear | Low |
| Özer et al (2011)43 | Low | Low | Low | Low | High | Low | Low |
| Yesildag et al (2011)44 | Unclear | Low | Low | Low | Low | Unclear | Low |
| Hsiao et al (2012)45 | Unclear | Low | Low | Low | Unclear | Low | Low |
| Previtali et al (2012)46 | Unclear | Low | Low | Low | Low | Unclear | Low |
| Arques, 201347 | Unclear | Low | Low | Low | Unclear | Unclear | Low |
| Manouras et al (2013)48 | Low | Low | Low | Low | Unclear | Unclear | Low |
| Weber et al (2013)49 | Low | Unclear | Unclear | Unclear | Unclear | Unclear | Low |
| Hajahmadi Poorrafsanjani et al (2014)50 | Low | Low | Low | Low | Unclear | Unclear | Low |
| Tatsumi et al (2014)51 | Unclear | Low | Low | Unclear | Unclear | Unclear | Low |
QUADAS‐2 questionnaire optimized to our study questions is presented below. QUADAS‐2 indicates Quality Assessment of Diagnostic Accuracy Studies 2.