Figure 2.

Interferon (IFN)β inhibits the production of proinflammatory cytokines in the ischemic brain. Ipsilateral and contralateral brain hemispheres from sham control, vehicle‐, and IFNβ‐treated middle cerebral artery occlusion/reperfusion (MCAO/R) mice (n=7/group) were harvested 24 hours after reperfusion. mRNA expression of interleukin (IL)‐1β, IL‐6, IL‐23p19, and TNF‐α was determined by quantitative polymerase chain reaction (Q‐PCR). Data are presented as the group mean±SEM. **P<0.01, ***P<0.001 by 1‐way ANOVA with Bonferroni's multiple comparison test.