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. 2016 Jan 25;5(1):e002856. doi: 10.1161/JAHA.115.002856

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© 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Histological analysis for myocardial infarction (MI) sizes in each group. Cardiac stem cells (CSCs)^Exo were preconditioned with 400 μg/mL mesenchymal stem cells (MSCs) for 24 hours, and CSCs were injected into the peri‐infarct zones after MI induction. Heart samples were harvested 28 days after cell injection. A, Heart sections were stained with Masson trichrome: myocardium (red), scarred fibrosis (blue). The percentage of fibrotic area (B) and fibrosis length (C) was calculated and averaged (n=5) by using Image J software.