Table 2.

a – Synthetic peptides of chemerin

Isoform	Sequence	Function of Isoform	Notes	Model	Ref
Chemerin-15	AGEDPHGYFLPGQFA	Mimics chemerin A154	Inhibit Macrophage	Mouse	18
FA Peptide	HSFYFPGQFA	Mimics chemerin A155	No Cell Chemotaxis	Human	16
11-mer	HSFYFPGQFAF	Mimics chemerin F156	Slight Cell Chemotaxis	Human	16
Chemerin-9	YFPGQFAFS	Mimics chemerin S157	Highest Biological Activity	Human Rat	14, 25
Chemerin-9	FLPGQFAFS	Mimics chemerin S158	Same potency as human	Mouse	22
10-mer	YFPGQFAFSK	Mimics chemerin K158	Inert	Human	19
15-mer	YFPGQFAFSKALPRS	Mimics chemerin S163	Inert	Human	16

Table 2b – Biologically derived peptides of chemerin
Isoform	ChemR23 Activity	Other	Model	Ref
Chemerin R125	Inert		Human	81
Chemerin F154	Inert		Human	20
Chemerin A155	Inert, antagonist of Chemerin-9	Most Abundant in Serum	Human	15, 16
Chemerin F156		Psoriasis	Human	56
Chemerin S157	Significant Ca2+ mobilization, chemotaxis	Most Active in Serum	Human	16, 80
Chemerin K158		Abundant in CSF and Synovial, Glioblastoma, RA	Human	16, 17
Chemerin S163	Prochemerin, inert		Human	15

A list of synthetic peptides are given with their sequence and are sorted based on the C-terminal amino acid of chemerin they were created to emulate. Chemerin-9 continues to be the primary agonist of the ChemR23 receptor (a). A list of biologically active isoforms is sorted according to their C-terminal amino acid. All are assumed to begin with amino acid E²¹. Although no full mouse isoforms are listed, full-length mouse peptides begin with E²³ [18] (b).