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. 2016 May 6;11(5):e0155217. doi: 10.1371/journal.pone.0155217

Fig 1. A cell proliferation based combination screening of α-Mangostin with kinase specific inhibitors.

Fig 1

A and B, show the screening scheme of primary screening and hit identification on SK-MEL-2 cell line. C, The dosage dependent cell proliferation assay of drugs and drug combination on SK-MEL-2 cells. D, The dosage dependent cell proliferation assay of drugs and drug combination on SK-MEL-30 cells. E, Synergistic effect of drug combination. CI (Combination Index) value at half lethal dosage IC50 indicated a strong synergistic effect of α-Mangostin and Sorafenib combination.