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. 2016 May 6;11(5):e0154584. doi: 10.1371/journal.pone.0154584

Table 3. Multivariate linear analyses for the effects of clinical characteristics, including chest CT parameters, on the 6MW distance (n = 217).

Clinical characteristics β P-value 95% CI
Model 1
    Age, years -2.915 < 0.001 -1.08 –-1.75
    BSA, m2 88.524 0.006 25.16–151.88
    FEV1, % predicted .138 0.694 -0.55–0.83
    FEV1/FVC, % .311 0.604 -0.87–1.49
    SGRQ, total score -1.388 < 0.001 -1.91 –-0.87
    mPA, mm -2.427 0.065 -5.00–0.15
Model 2
    Age, years -3.322 < 0.001 -4.53 –-2.11
    BSA, m2 65.785 0.047 0.80–130.77
    FEV1, % predicted .194 0.583 -0.50–0.89
    FEV1/FVC, % .289 0.632 -0.89–1.47
    SGRQ, total score -1.403 < 0.001 -1.93 –-0.88
    Ao, mm 1.469 0.245 -1.02–3.95
Model 3
    Age, years -3.162 < 0.001 -4.31 –-2.02
    BSA, m2 76.917 0.015 15.19–138.65
    FEV1, % predicted .181 0.603 -0.51–0.87
    FEV1/FVC, % .262 0.66 -0.91–1.43
    SGRQ, total score -1.389 < 0.001 -1.91 –-0.87
    mPA/Ao ratio -107.717 0.017 -195.69 –-19.74

CT, computed tomography; 6MW, 6-minute walking; CI, confidence interval; BSA, body-surface area; FEV1, forced expiratory volume in 1s; FVC, forced vital capacity; SGRQ, St. George's Respiratory Questionnaire; mPA, main pulmonary artery diameter; Ao, aorta diameter.