Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 6;11(5):e0155215. doi: 10.1371/journal.pone.0155215

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Bissonnette et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig 4 — Heat map representing the expression profiles of the top 75 PPP/PPPP specific (A) and psoriasis specific (B) genes. The psoriasis PPP (P) specific genes are those that are differentially expressed in the PPP/PPPP versus normal acral skin and not differentially expressed in the psoriasis versus normal non-acral skin (FDR<0.05; FCH>2 in both comparisons). Likewise psoriasis specific genes are those that are differentially expressed in psoriasis as compared with normal non-acral skin but are not differentially expressed in the PPP/PPPP versus normal acral skin comparisons. In both cases the top 75 are selected based on the largest differences observed between the log2FCH of the PPP/PPPP vs acral and the psoriasis versus non-acral skin comparison. The expression of several genes, including ADAM23 and GPRIN, is higher in PPP/PPPP (lower left portion of Fig 5A) Genes are presented according to an unsupervised cluster analysis. Yellow-red scale: red represents low gene expression and yellow high gene expression.