FIG 3.
Monkeys immunized with different HIV-1 Env immunogens generate antibodies that neutralize HIV-1JR-FL sensitized with BNM-III-170. Recombinant, luciferase-expressing viruses with HIV-1JR-FL Env or A-MLV Env were incubated with 30 μM BNM-III-170 (green) or without compound (red). The viruses subsequently were incubated with the indicated dilution of plasma from immunized monkeys prior to incubation with Cf2Th-CD4/CCR5 cells for 48 h. The level of infection relative to that seen in the absence of plasma is shown. The means and standard deviations from triplicate samples in a typical experiment are shown.