FIG 6.
Cooperativity in HIV-1 inhibition between a CD4-mimetic compound and antibodies. Recombinant, luciferase-expressing viruses with HIV-1JR-FL Env (A, C, and D) or A-MLV Env (B) were incubated with the indicated concentrations of BNM-III-170, followed by incubation with the indicated concentration of either the 17b antibody (A and B) or the indicated dilution of plasma from two monkeys in CHAVI-ID NHP 62.1 (C and D). The viruses were used to infect Cf2Th-CD4/CCR5 cells, and the level of infection was measured as described in Materials and Methods. The means and standard deviations from triplicate samples are shown.