FIG 5.
Inflammation associated with A2 and A2(91G) infections differentially promotes CD8 T cell expansion. (Left) Experimental setup. A total of 2 × 105 BMDCs pulsed with LT206 peptide were injected i.v. into the tail vein in B6 mice. Three hours later, mice were inoculated with 1.0 × 106 PFU of A2 or A2(91G) in the hind footpads. (Right) The frequency of DbLT206 tetramer+ CD8 T cells in blood was analyzed at the indicated days p.i. Data were combined from three independent experiments with three mice per group. Values indicate means and SEM. **, P < 0.005; NS, not significant.