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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: J Struct Biol. 2016 Apr 13;194(3):446–450. doi: 10.1016/j.jsb.2016.04.003

Fig. 1. Structure of DeoxyHb S (PDB code 2HBS).

Fig. 1

(A) Ribbon figure of the crystal packing of deoxyHb S. (B) The pathological β2Val6 in one strand (blue) interacts with a hydrophobic pocket formed by β1Ala70, β1Phe85, and β1Leu88 from the β1 subunit of a heterotetramer positioned in the adjacent polymeric strand (green). This interaction is stabilized by a hydrogen-bond contact between β2Thr4 and β1Asp73.