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. 2016 Mar 22;34:347–354. doi: 10.1007/s10637-016-0347-6

Fig. 2.

Fig. 2

PK parameters versus dose following the first administration of pembrolizumab in Japanese and non-Japanese patients with advanced solid tumors. AUC 0-∞ total area under the concentration–time curve, C max maximum concentration, CL clearance, Vz the terminal phase volume