Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
M2698 reduced tumor burden and prolonged survival in the U251 human glioblastoma xenograft mouse model. Mice bearing U251 orthotopic tumors were treated with vehicle (n=9) or M2698 25 mg/kg qd po (n=10) from Day 18 (when mean tumor mass was 6 mg) until Day 50 (end of study). A. MRI was performed on Days 17 and 31. Representative images are shown. B. Group survival curves of tumor-bearing animals treated with vehicle or M2698 25 mg/kg. qd po. po, oral administration; qd, once daily.
