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PP2A B subunits changed and Akt/GSK3β/β-catenin pathway disrupted. A. Quantitative real-time PCR assay was carried out to examine the expression levels of PP2ACb genes. B. Western blot of AKT, P-AKT (S473), P-AKT (T308), phospho-GSK3β (ser9), β-catenin, P-β-catenin (Ser552) from mice heart protein extracts from the knockout group and the control group 10 days after tamoxifen injection. C. Statistical analysis for the western blot. n ≥ 6 in each group,*P < 0.05, **P < 0.01.
