Table 2.

Comparison of clinical scores in EAE (X ± SD)

Group	n	Treatment	Before treatment	After treatment
A	7	estrogen	2.57±0.79	0.67±0.52*
B	7	high-dose ICA	2.42±0.67	1.25±0.29#
C	6	mid-dose ICA	2.75±1.33	1.88±0.75
D	6	low-dose ICA	1.83±0.75	1.70±1.20
E	6	mid-dose ICA and ICI 182780	1.92±0.80	2.25±0.87#
M	6	placebo	2.08±0.86	2.25±1.33#

Vs. before treatment;

^* P<0.01;

^# P<0.05 (Wilcoxon signed rank test).

There was no significant difference in clinical score changes between estrogen and high-dose ICA groups (Mann-Whitney u test).