Table 2.
Gefitinib Related Adverse Events.
| TOXICITY TYPE | GRADE(#) | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | Total | |
| Hemoglobin | 0 | 3 | 0 | 0 | 3 |
| Neutrophils | 0 | 0 | 1 | 3 | 4 |
| Platelets | 2 | 0 | 0 | 1 | 3 |
| Fatigue | 4 | 0 | 0 | 0 | 4 |
| Weight loss | 1 | 0 | 0 | 0 | 1 |
| Dry skin | 1 | 0 | 0 | 0 | 1 |
| Rash/desquamation | 0 | 4 | 0 | 0 | 4 |
| Anorexia | 1 | 1 | 0 | 0 | 2 |
| Constipation | 1 | 0 | 0 | 0 | 1 |
| Diarrhea w/o prior colostomy | 6 | 2 | 4 | 0 | 12 |
| Muco/stomatitis (symptom) oral cavity | 1 | 0 | 0 | 0 | 1 |
| Nausea | 3 | 0 | 1 | 0 | 4 |
| Vomiting | 2 | 0 | 1 | 0 | 3 |
| GI-other | 1 | 0 | 0 | 0 | 1 |
| Infection Gr0-2 neut, skin | 0 | 1 | 0 | 0 | 1 |
| Hypoalbuminemia | 0 | 1 | 0 | 0 | 1 |
| Alkaline phosphatase | 2 | 0 | 0 | 0 | 2 |
| ALT, SGPT | 1 | 1 | 1 | 0 | 3 |
| AST, SGOT | 5 | 0 | 0 | 0 | 5 |
| Bicarbonate | 0 | 1 | 0 | 0 | 1 |
| Bilirubin | 1 | 1 | 0 | 0 | 2 |
| Hypocalcemia | 2 | 0 | 0 | 0 | 2 |
| Creatinine | 1 | 0 | 0 | 0 | 1 |
| Hyperglycemia | 3 | 0 | 0 | 0 | 3 |
| Hypomagnesemia | 1 | 0 | 0 | 0 | 1 |
| Hypokalemia | 1 | 0 | 1 | 0 | 2 |
| Hyperuricemia | 2 | 0 | 0 | 0 | 2 |
| Dizziness | 2 | 0 | 0 | 0 | 2 |
| Tearing | 0 | 1 | 0 | 0 | 1 |
| Oral cavity, pain | 0 | 1 | 0 | 0 | 1 |
| Cough | 1 | 0 | 0 | 0 | 1 |