Table 1.
Normal (n=126) | MPS (n=117) | PS (n=26) | ||
---|---|---|---|---|
Demographics# | Age (years)* | 74.41 (6.12) | 77.50 (6.72) | 81.23 (5.93) |
Education (years) | 14.44 (3.00) | 14.36 (3.08) | 13.81 (2.40) | |
% Female | 55.00 | 57.00 | 58.00 | |
% Caucasian | 89.00 | 83.00 | 96.00 | |
GHS score (0–10) | 0.99 (0.97) | 1.26 (1.26) | 1.39 (0.94) | |
GDS score (0–30)\widehat | 4.12 (3.14) | 4.90 (4.04) | 6.15 (3.88) | |
RBANS total standard score (55–145)¥ | 93.75 (11.10) | 89.82 (12.85) | 91.04 (11.12) | |
MPS Domains# | Bradykinesia (% present) | 0.00 | 31.00 | 100.00 |
Rigidity (% present) | 0.00 | 63.00 | 100.00 | |
Tremor (% present) | 0.00 | 9.00 | 15.00 | |
PIGD (% present) | 0.00 | 32.00 | 50.00 | |
MPS severity score (0–36) | 0.00 (0.00) | 3.21 (2.49) | 11.08 (3.60) | |
fNIRS# | Mean HbO2 value | 0.03 (0.21) | 0.07 (0.21) | 0.05 (0.27) |
Balance# | COP velocity (cm/s) | 1.51 (3.14) | 1.56 (1.92) | 2.82 (7.45) |
Abbreviations: MPS=mild parkinsonian signs; PS=parkinsonian syndrome; PIGD=postural instability and gait disturbances; GHS=global health score; GDS=geriatric depression scale; RBANS=Repeatable Battery for the Assessment of Neuropsychological Status; HbO2 =oxygenated hemoglobin averaged across 16 channels and 8 second recording time; COP=Center of pressure average across 8 second recording time.
Mean (SD) unless otherwise noted.
Group differences in demographics: significant difference at the p<0.01 for all group comparisons (normal vs. MPS, normal vs. PS, & MPS vs. PS).
\widehat: Group differences in demographics: significant difference at the p<0.01 for normal vs. PS.
Group differences in demographics: significant differences at the p<0.01 for normal vs. MPS.