Table 3.
Baseline characteristics of older adults with MDS by treatment group.
| Characteristic | No chemotherapy (N = 53) |
Non-intensive chemotherapy (N = 44) |
Intensive chemotherapy (N = 17) |
|---|---|---|---|
|
| |||
| N (%)a | |||
| Age category | |||
| 65–69 | 12 (22.6) | 11 (25.0) | 11 (64.7) |
| 70–74 | 10 (18.9) | 19 (43.2) | 6 (35.3) |
| 75–79 | 15 (28.3) | 7 (15.9) | 0 |
| 80+ | 16 (30.2) | 7 (15.9) | 0 |
| Male | 39 (73.6) | 31 (70.5) | 15 (88.2) |
| White | 52 (98.1) | 40 (90.9) | 16 (94.1) |
| Lives alone | 9 (17.0) | 4 (9.1) | 0 |
| History of tobacco use | 31 (58.5) | 22 (50.0) | 5 (29.4) |
| WHO BMI categories | |||
| <25 | 16 (31.4) | 12 (27.9) | 2 (11.8) |
| 25–30 | 23 (45.1) | 16 (37.2) | 9 (52.9) |
| >30 | 12 (23.5) | 15 (34.9) | 6 (35.3) |
| Baseline Charlson comorbidity score | 17 (32.1) | 16 (36.7) | 10 (58.8) |
| 0 | 7 (13.2) | 9 (20.5) | 3 (17.7) |
| 1 | 16 (30.2) | 11 (25.00) | 3 (17.7) |
| 2 | 13 (24.5) | 8 (18.2) | 1 (5.9) |
| ≥3 | |||
| Baseline ECOG PS | |||
| 0 | 20 (37.8) | 22 (50.0) | 9 (52.9) |
| 1 | 28 (52.8) | 17 (38.6) | 4 (23.5) |
| ≥2 | 5 (9.4) | 5 (11.3) | 4 (23.5) |
| Serum albumin <3.5 g/dl | 7 (13.2) | 4 (9.1) | 0 (0.0) |
| Number of cytopenias | |||
| 0 | 10 (18.9) | 4 (1) | 2 (11.8) |
| 1 | 19 (35.9) | 12 (27.3) | 5 (29.4) |
| 2 | 15 (28.3) | 19 (43.2) | 5 (29.4) |
| 3 | 9 (17.0) | 9 (20.5) | 5 (29.4) |
| Bone marrow blasts | |||
| <5% | 44 (86.3) | 21 (47.7) | 9 (52.9) |
| 5–10% | 5 (9.8) | 16 (36.4) | 6 (35.3 |
| >10% | 2 (3.9) | 7 (15.9) | 3 (11.8) |
| IPSS category | |||
| Low risk | 20 (37.7) | 5 (11.4) | 2 (11.8) |
| Intermediate risk-1 | 26 (49.1) | 19 (43.2) | 7 (41.2) |
| Intermediate risk-2 | 5 (9.4) | 17 (38.6) | 8 (47.1) |
| High risk | 2 (3.8) | 3 (6.8) | 0 (0.00) |
| Previous chemotherapy or radiation | 11 (20.8) | 9 (20.5) | 0 (0.00) |
a
May not add up to 100% due to missing variables.