Table 5.
Characteristic | Variable | Median OS (months) |
Log-rank p valuea |
1-year OS (%surviving) |
2-year OS (%surviving) |
---|---|---|---|---|---|
Age | Age at diagnosis | ||||
≤72.5 | 21 ± 1.51 | 0.49 | 62 ± 0.62 | 48 ± 1.78 | |
>72.5 | 25 ± 1.98 | 68 ± 0.77 | 53 ± 1.80 | ||
Disease specific factors | IPSS score | 0.001 | |||
Lower risk (score 0–1) | 35 ± 2.59 | 74 ± 0.61 | 64 ± 1.44 | ||
Higher risk (score > 1) | 12 ± 1.08 | 45 ± 1.07 | 22 ± 1.90 | ||
Previous chemo/radiation | |||||
No | 26 ± 1.56 | 0.020 | 68 ± 0.6 | 55 ± 1.37 | |
Yes | 9 ± 1.08 | 48 ± 1.45 | 27 ± 2.81 | ||
Comorbidities/risk factors | Charlson score | ||||
<3 | 29 ± 2.70 | 0.043 | 78 ± 0.79 | 66 ± 1.87 | |
≥3 | 14 ± 0.90 | 57 ± 0.74 | 41 ± 1.61 | ||
Nutrition | Serum albumin | 0.005 | |||
≥3.5 g/dl | 26 ± 2.4 | 67 ± 0.59 | 52 ± 1.32 | ||
<3.5 g/dl | 4 ± 0.6 | 45 ± 1.80 | 14 ± 3.2 | ||
Vomiting in the past week | 0.022 | ||||
None | 26 ± 1.48 | 68 ± 0.56 | 53 ± 1.30 | ||
Some | 8.5 ± 1.73 | 25 ± 2.45 | 0 | ||
Physical function | Trouble taking a long walk | 0.006 | |||
None | 53b | 79 ± 0.92 | 71 ± 2.09 | ||
Some | 21 ± 1.28 | 61 ± 0.68 | 43 ± 1.49 | ||
Social function | Effect of physical symptoms on family life | 0.024 | |||
None | 36 ± 3.10 | 73 ± 0.67 | 57 ± 1.58 | ||
Some | 14 ± 1.12 | 52 ± 0.95 | 39 ± 1.94 |
Derived from the Log-Rank test.
Median survival not reached by 53 months of follow-up.