Table 3.
Significant genetic association with SGA, RDS and CPV
Gene rs number |
Outcome | Odds Ratio with 95% confidence interval, (p-value) |
Strongest Genetic Model |
---|---|---|---|
CRHBP rs10062367 |
SGA | 2.04 [1.12, 3.71] (0.019) |
Additive |
CRH rs2446432 |
SGA | 2.88 [1.03, 8.07] (0.044) |
Dominant |
CRHR1 rs7225082 |
SGA | 3.42 [1.22, 9.58] (0.019) |
Dominant |
HSD11B1 rs2282739 |
RDS | 2.09 [1.08, 4.05] (0.030) |
Additive |
SCNN1B rs239349 |
RDS | 3.18 [1.08, 9.42] (0.036) |
Dominant |
CRH rs2446432 |
CPV | 0.44 [0.20, 0.97] (0.041) |
Dominant |
SerpinA6 rs3748320 |
CPV | 2.35 [1.02, 5.37] (0.044) |
Dominant |
CRHR1 rs7225082 |
CPV | 0.39 [0.17, 0.91] (0.029) |
Dominant |
The referent group is without minor alleles