Table 4.
Interaction effect of single versus multiple dose steroids and genotype
Strongest Genetic Model |
Gene rs number |
Outcome (interaction p-value) |
Single Course with minor alleles |
Multiple Courses without minor alleles |
Multiple Courses with minor alleles |
---|---|---|---|---|---|
Additive Model |
SerpinA6 rs3748320 |
RDS (0.019) |
0.44 [0.11, 1.81] | 0.30 [0.09, 0.95] | 1.29 [0.43, 3.91] |
Dominant Model |
SCNN1B rs239349 |
CPV (0.040) |
0.87 [0.32, 2.41] | 0.08 [.009, 0.66] | 0.78 [0.28, 2.18] |
The referent group is single course steroids without minor alleles. Results for comparison with single course and multiple courses are Odds ratios with 95% confidence intervals.