Table 2. Univariate associations with anxiety, depression, and combined symptoms.
| Anxiety | Depression | Both Anx & Dep | ||||
|---|---|---|---|---|---|---|
| OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | P | |
| Caregiver's age | 0.96(0.86,1.07) | 0.370 | 0.97(0.90,1.05) | 0.353 | 0.91(0.81,1.03) | 0.110 |
|
| ||||||
| Age at diagnosis | ||||||
| Pre-school (2-4) | Reference group | Reference group | Reference group | |||
| School-age (5-12) | 0.30(0.03,3.08) | 0.157 | 0.68(0.15,3.16) | 0.395 | 0.68(0.06,7.81) | 0.564 |
|
| ||||||
| Child's sex | ||||||
| Male | 1.42(0.15,13.23) | 0.568 | 0.89(0.20,4.10) | 0.779 | 1.39(0.12,15.52) | 0.617 |
| Female | ||||||
|
| ||||||
| Child Race/Ethnicity | ||||||
| White, non- Hispanic | Reference group | Reference group | Reference group | |||
| Hispanic | 3.96(0.29,50.81) | 0.153 | 0.93(0.10,8.39) | 0.897 | 4.34(0.21,87.15) | 0.170 |
| Black, non-Hispanic | 0.49(0.01,126.4) | 0.634 | 1.91(0.11,31.96) | 0.426 | 0.77(0.01,162.2) | 0.853 |
| Other | 0.68(0.01,50.17) | 0.733 | 0.92(0.06,13.90) | 0.904 | 4.12(0.09,186.2) | 0.249 |
|
| ||||||
| Primary language | ||||||
| English | Reference group | Reference group | Reference group | |||
| Spanish | 4.09(0.79,21.64) | 0.083 | 0.54(0.12,2.52) | 0.374 | 6.28(1.03,38.4) | 0.047 |
|
| ||||||
| Annual family income | ||||||
| ≥$50,000 | Reference group | Reference group | Reference group | |||
| <$50,000 | 0.55(0.16,1.93) | 0.284 | 0.93(0.36,2.38) | 0.854 | 1.74(0.39,7.69) | 0.397 |
|
| ||||||
| Maternal education | ||||||
| Some college | Reference group | Reference group | Reference group | |||
| Less than college | 1.39(0.42,4.64) | 0.550 | 0.91(0.38,2.15) | 0.802 | 2.24(0.65,7.68) | 0.174 |
|
| ||||||
| Marital status | ||||||
| Married | Reference group | Reference group | Reference group | |||
| Not married | 0.53(0.10,2.99) | 0.41 | 0.87(0.28,2.68) | 0.78 | 0.99(0.18,5.43) | 0.99 |
|
| ||||||
| General Family Functioning (FAD) | ||||||
| Healthy function | Reference group | Reference group | Reference group | |||
| Unhealthy function | 1.98(0.61,6.43) | 0.225 | 2.62(1.61,5.92) | 0.024 | 4.43(1.19,16.43) | 0.030 |
|
| ||||||
| Family size | 1.37(0.93,2.04) | 0.099 | 1.04(0.75,1.44) | 0.792 | 1.17(0.74,1.88) | 0.436 |
|
| ||||||
| Maintaining family integration (CHIP) | 0.99(0.94,1.05) | 0.779 | 0.96(0.92,1.01) | 0.081 | 0.96(0.90,1.03) | 0.205 |
|
| ||||||
| Maintaining social support (CHIP) | 1.00(0.95,1.06) | 0.890 | 0.97(0.93,1.01) | 0.152 | 0.93(0.88,0.99) | 0.027 |
|
| ||||||
| Understanding medical situation (CHIP) | 1.04(0.93, 1.17) | 0.473 | 0.97(0.89, 1.05) | 0.384 | 0.96(0.85, 1.09) | 0.484 |
|
| ||||||
| Pain and hurt (PedsQL) | 0.99(0.96, 1.01) | 0.193 | 0.99(0.97, 1.01) | 0.156 | 0.98(0.96, 1.01) | 0.113 |
|
| ||||||
| Nausea (PedsQL) | 0.98(0.95, 1.02) | 0.319 | 0.99(0.97, 1.02) | 0.450 | 0.98(0.94, 1.02) | 0.205 |
|
| ||||||
| Therapeutic arm1 | ||||||
| SC/SIM-SDI | Reference group | Reference group | Reference group | |||
| IC/SIM-SDI | 3.99(0.18,89.97) | 0.196 | 1.25(0.15,10.37) | 0.692 | 0.77(0.03,18.77) | 0.757 |
| SC/AIM-ADI | 1.67(0.05,51.71) | 0.587 | 1.38(0.15,12.44) | 0.597 | 1.16(0.04,32.65) | 0.869 |
| IC/AIM-ADI | 2.60(0.08,86.75) | 0.361 | 2.20(0.22,21.74) | 0.276 | 0.72(0.02,31.86) | 0.752 |
|
| ||||||
| Neurological event on therapy | ||||||
| No | Reference group | Reference group | Reference group | |||
| Yes | 0.67(0.11,4.16) | 0.661 | 2.99(1.04,8.58) | 0.042 | 2.72(0.38,19.39) | 0.309 |
1
SC=Standard Consolidation, IC=Intensified Consolidation, SIM-SDI=Standard Interim Maintenance and Standard Delayed Intensification, AIM-ADI=Augmented Interim Maintenance and Augmented Delayed Intensification