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. Author manuscript; available in PMC: 2017 May 5.
Published in final edited form as: Mol Cell. 2016 Apr 21;62(3):335–345. doi: 10.1016/j.molcel.2016.03.021

Figure 4. METTL3 recruits eIF3 to the translation initiation complex.

Figure 4

(A–E) Co-IPs of indicated FLAG-tagged proteins analyzed by Western blot using the indicated antibodies. Where indicted lysates were treated with RNase A. (E) Co-IPs performed using lysates collected from either control- or METTL3 siRNA transfected cells. (F) Western blot performed on cell lysates collected from indicated cells transfected with control-, METTL3-, or YTHDF1 siRNA. See also Figure S4.