Figure 5. METTL3 promotes translation by recruiting translation initiation factors.
(A) Schematic diagram of tethering reporter assay. (B) α-FLAG western blot of indicated proteins. (C) Tethering assay to measure translation efficiency of reporter mRNAs. FLuc activity was measured and normalized to the RLuc activity. ***P<0.001. Error bars = mean ±s.d., n=3.