Figure 6.
Ventral and dorsal cochlear nuclei expression patterns at P4 for ephrin-B2 (A, B), EphA4 (C, D), and ephrin-B3 (E, F). Ephrin-B2 is uniformly expressed throughout the VCN and DCN, albeit lacking in the overlying molecular layer (A, B). EphA4 expression is not uniform, but graded, with protein increasingly concentrated in more dorsal, high-frequency regions (C, D; white arrows). Complementary to ephrin-B2, VCN and DCN are largely devoid of ephrin-B3 protein (E, F), aside from positive label confined to the molecular layer and nonuniform expression in the auditory nerve root (VIII). Dashed contours represent nuclear boundaries. Scale bars = 200 μm.