Activated microglia/macrophages within the hippocampus and dentate gyrus of antagonist-treated mice. TMEV-infected C57BL/6J mice were treated with MK 801, GYKI-52466 and NBQX or with PBS as a control (treatment: day 2.5–10.5 post infection). Mice were sacrificed on day 21 post infection. RCA-1+ cells were enumerated as described in the Methods. The number of mice in each group is given as N above each column. Data is given as mean + SEM. †p<0.05, *p<0.01, **p<0.001, ‡p<0.0001, ANOVA and Fisher’s PLSD.