Figure 6.
n-3 PUFAs inhibit MMP activation after neonatal H/I. (A) Gelatin zymography shows MMP-9 and MMP-2 activity in brain tissue at 48 hours after H/I. (B) Quantification of MMP-9 and MMP-2 activity in the brain. (C) Representative immunofluorescent images of gelatinolytic activity (green) and NeuN, GFAP, and lectin (red) at 48 hours post H/I. Nuclei were stained with DAPI (blue; scale bar=20µm). **p≤0.01; ***p≤0.001 vs Sham, ##p≤0.01; ###p≤0.001 vs N3L H/I, data are mean± s.d., n=6 each group.