Table 3.
Unadjusted and adjusted ORs for the association of symptoms and laboratory findings with severe asthma exacerbations
| Predictor | No. of patients | Unadjusted OR (95% CI) | Adjusted ORa (95% CI) |
|---|---|---|---|
| Overweight or obese | 434 | 1.90 (1.15-3.15) | 1.57 (0.92-2.67) |
| Cough with phlegm | 434 | 2.47 (1.48-4.12) | 2.38 (1.39-4.07) |
| Muscle pain | 434 | 0.38 (0.23-0.63) | 0.39 (0.23-0.67) |
| Eye symptoms | 434 | 0.43 (0.26-0.71) | 0.42 (0.25-0.70) |
| Gastrointestinal symptoms | 434 | 0.32 (0.18-0.56) | 0.36 (0.20-0.65) |
| Hyperemic pharynx | 434 | 0.22 (0.13-0.37) | 0.25 (0.14-0.43) |
| Leukocytosis | 425 | 6.09 (3.43-10.82) | 7.15 (3.85-13.30) |
| Neutrophilia | 398 | 2.58 (1.39-4.79) | 2.74 (1.42-5.29) |
| Lymphocytopenia | 409 | 4.11 (2.32-7.27) | 4.47 (2.43-8.23) |
| Time from onset to seeking medical attention, d | |||
| 0-1 vs 2-3 | 433 | 2.85 (1.46-5.58) | 2.93 (1.46-5.88) |
| 0-1 vs ≥4 | 4.99 (2.19-11.36) | 5.32 (2.18-12.98) | |
Abbreviations: CI, confidence interval; OR, odds ratio.
a
Logistic regression model 1 was adjusted for age, sex, and current smoke exposure. All remaining models were adjusted for age, sex, current smoke exposure, and overweight or obese status.