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. Author manuscript; available in PMC: 2016 May 7.
Published in final edited form as: Stem Cells. 2016 Feb 1;34(5):1284–1296. doi: 10.1002/stem.2283

Figure 6.

Figure 6

YAP1 inhibition induces hepatocytic differentiation in HepaRG cells. (A): YAP1 mRNA and protein expression levels determined respectively by quantitative PCR (left panel) and western blot analysis (right panel) in HepaRG-empty and HepaRG-YAP1 KD cell lines. α-tubulin was used to control protein loading. (B): Mean bile canaliculi densities of HepaRG-empty and HepaRG-YAP1 KD cell lines assessed from three randomly selected fields in two independent experiments. (C): Relative expression levels of HNF4A at day 14 and of HNF4A, ALDOB, CYP3A4 and ALB at day 28 of hepatocytic differentiation process in HepaRG-YAP1 KD compared to HepaRG-empty cell lines.