Table 3.

Genetic Risk For Leading Causes of Death with a Component.

	Wellderly Genetic Risk	ITMI Genetic Risk	Wellderly Odds Ratio	p-value
Alzheimer disease	0.0075 (±0.0418)	0.1060 (±0.0409)	0.906 (±0.051)	0.009
Breast Cancer	0.596 (±0.045)	0.600 (±0.045)	0.996 (±0.064)	1.0
Colorectal Cancer	1.11 (±0.030)	1.12 (±0.03)	0.992 (±0.032)	1.0
Coronary Artery Disease	8.27 (±0.035)	8.35 (±0.040)	0.922 (±0.047)	0.023
Lung Cancer	0.130 (±0.027)	0.142 (±0.022)	0.988 (±0.034)	1.0
Pancreatic Cancer	0.364 (±0.033)	0.387 (±0.026)	0.977 (±0.040)	1.0
Prostate Cancer	4.80 (±0.100)	4.75 (±0.090)	1.050 (±0.131)	1.0
Stroke	2.04 (±0.030)	2.09 (±0.030)	0.958 (±0.043)	0.66
Type 2 Diabetes	6.40 (±0.050)	6.39 (±0.04)	1.004 (±0.0580)	1.0

Mean genetic risk score is presented with 95% confidence interval in parenthesis. Wellderly odds ratio is the overall odds ratio of Wellderly individuals for the development of each disease relative to the general population – also with 95% confidence interval in parenthesis. p-values corrected for multiple testing are reported. See also Supplemental Table S3