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. Author manuscript; available in PMC: 2016 Oct 11.
Published in final edited form as: Nat Med. 2016 Apr 11;22(5):524–530. doi: 10.1038/nm.4075

Figure 5. Cholera toxin promotes Nod2 activation via cAMP/PKA signaling.

Figure 5

(a) Concentration of cytokines in the supernatant of BMDC (measured in triplicate) treated with the indicated stimuli for 24 h. (b) Concentration of cytokines in the supernatant of BMDM (measured in triplicate) treated with 8-Br-cAMP (cAMP), N6-benzoyl-cAMP (Bnz-cAMP), or 8-CPT-2'-O-Me-cAMP (CPT-cAMP) in the presence or absence of MDP for 24 h. The results are representative of at least three independent sets of experiments. Data are expressed as the mean ± s.d. ***P < 0.001 by Student’s t-test.