Table 1a.
Prevalence (n [%]) of familial factors for MSDP-E by propensity quartile
| Familial factors |
Overall1
|
by Quartile1
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No MSDP (N=514) |
MSDP-E (N=414) |
0–25 %ile
|
26–50 %ile
|
51–75 %ile
|
76–100 %ile
|
||||||
| No MSDP (N=183) |
MSDP-E (N=41) |
No MSDP (N=150) |
MSDP-E (N=89) |
No MSDP (N=115) |
MSDP-E (N=117) |
No MSDP (N=66) |
MSDP-E (N=167) |
||||
|
|
|
|
|
|
|||||||
| Race (Black) | 65 (13%) | 69 (17%) | 12 (7%) | 6 (15%) | 17 (11%) | 10 (11%) | 18 (16%) | 23 (20%) | 18 (27%) | 30 (18%) | |
| Paternal Smoking | 300 (58%) | 234 (57%) | 124 (69%) | 18 (47%) | 81 (56%) | 41 (53%) | 59 (56%) | 73 (67%) | 36 (69%) | 102 (70%) | |
| Maternal Education | >13 | 261 (51%) | 177 (43%)* | 106 (59%) | 29 (71%) | 87 (58%) | 46 (52%) | 52 (45%) | 59 (51%) | 16 (24%) | 43 (26%) |
| Paternal Education | >13 | 225 (44%) | 166 (40%) | 91 (53%) | 16 (39%) | 62 (42%) | 37 (44%) | 52 (47%) | 52 (44%) | 20 (30% | 61 (39%) |
| Maternal FTND severitya: | 0 | 134 (26%)‡ | 46 (11%)‡ | 102 (60%) | 20 (57%)‡ | 30 (20%) | 18 (20%)‡ | 2 (2%) | 8 (7%) | 0 (0%) | 0 (0%)† |
| 1 | 154 (30%) | 107 (26%)** | 28 (17%) | 10 (29%) | 61 (41%) | 27 (30%) | 49 (43%) | 46 (39%) | 16 (24%) | 24 (14%) | |
| 2 | 115 (22%) | 95 (23%)** | 31 (18%) | 2 (6%) | 38 (25%) | 36 (40%) | 36 (32%) | 39 (33%) | 10 (15%) | 18 (11%) | |
| 3 | 79 (15%) | 136 (33%)*** | 8 (5%) | 3 (9%) | 15 (10%) | 8 (9%) | 22 (19%) | 19 (16%) | 34 (51%) | 106 (63%) | |
| 4 | 16 (3%) | 24 (6%)** | 0 (0%) | 0 (0%)† | 6 (4%) | 0 (0%)† | 4 (4%) | 5 (4%)‡ | 6 (9%) | 19 (11%)‡ | |
| Paternal AD | 3+ sx | 97 (19%) | 121 (29%)* | 21 (11%) | 6 (15%) | 22 (15%) | 12 (13%) | 26 (23%) | 27 (23%) | 28 (42%) | 76 (46%) |
| Maternal AD | 3+ sx | 28 (5%) | 22 (5%) | 4 (2%) | 0 (0%)† | 10 (7%) | 4 (4%) | 12 (10%) | 2 (2%) | 2 (3%) | 16 (10%) |
| Maternal Ageb: | ≤20 | 58 (11%) | 63 (15%) | 20 (11%) | 8 (20%) | 8 (5%) | 12 (13%) | 14 (12%) | 13 (11%) | 16 (24%) | 30 (18%) |
| ≤30 | 206 (40%) | 137 (33%) | 80 (44%) | 14 (34%) | 66 (44%) | 39 (44%) | 40 (35%) | 49 (42%) | 20 (30%) | 35 (21%)* | |
| ≤35 | 79 (15%) | 58 (14%) | 33 (18%) | 10 (24%) | 24 (16%) | 12 (13%) | 14 (12%) | 24 (21%) | 8 (12%) | 12 (7%) | |
| >35 | 25 (5%) | 13 (3%) | 13 (7%) | 1 (2%) | 10 (7%) | 5 (6%) | 2 (2%) | 0 (0%)† | 0 (0%) | 7 (4%)† | |
| Maternal Year of Birthc: | ≤1949 | 114 (22%) | 75 (18%) | 52 (28%) | 9 (22%) | 34 (23%) | 18 (20%) | 16 (14%) | 20 (17%) | 12 (18%) | 28 (27%) |
| ≤1959 | 169 (33%) | 166 (40%) | 47 (26%) | 10 (24%) | 39 (26%) | 32 (36%) | 47 (41%) | 40 (34%) | 36 (55%) | 84 (50%) | |
| ≥1960 | 74 (14%) | 67 (16%) | 28 (15%) | 10 (24%) | 18 (12%) | 12 (13%) | 20 (17%) | 12 (10%) | 8 (12%) | 33 (20%) | |
| Parents Never Together | 32 (6%) | 33 (8%) | 12 (8%) | 4 (11%) | 6 (4%) | 4 (5%) | 8 (9%) | 5 (4%) | 6 (12%) | 20 (15%) | |
Characteristics of individuals from mothers with (MSDP-T)/without (no-MSDP) a history of smoking during the first trimester for each quartile of the MSDP-T risk distribution. Notation: proportion and percentages reported are relative to the total sample size for the given category for “No MSDP” or MSDP-T;
p<.001;
p < .01;
p<05; sx = symptom;
Logistic regressions performed on the overall sample or within quartile to examine relationship between MDSP and familial factors;
Reference group for the multinomial logistic regression is FTND=1 for Overall, Q1, and Q2 but is FTND=4 for Q3 and Q4 due to low cell counts;
Reference group for the multinomial logistic regression is maternal age 21–25;
Reference group for the multinomial logistic regression is maternal year of birth 1950–1954;
can’t compute difference due to cell size 0;
used as reference group.