Table 3a.

Effect (β [95% confidence interval]) of MSDP-E on offspring externalizing behavior

Phenotype	Model-I	Model-II		βMSDP-Eb by quartile
	βMSDP-E	βMSDP-E	βP-SCORE	0–25%ile	26–50%ile	51–75%ile	76–100%ile
ADHD IN	0.95 [0.48,1.41]***	0.32 [−0.74,1.39]	0.81 [0.08,1.55]a	0.85 [0.38, 1.32]**	−0.36 [−1.29, 0.57]	0.28 [−0.35, 0.91]	−0.54 [−1.41, 0.33]
ADHD HI	0.68 [0.14,1.21]*	0.18 [−0.38,0.75]	0.78 [0.38,1.17]**	0.63 [0.09, 1.18]a	0.70 [0.31, 1.09]*	−0.39 [−1.34, 0.56]	−0.74 [−1.17, −0.32]**
CD	0.45 [0.17,0.72]**	0.43 [0.10,0.76]*	0.05 [−0.30,0.41]	0.67 [0.16, 1.17]*	0.24 [−0.04, 0.51]	0.31 [−0.25, 0.88]	0.19 [−0.93, 1.31]
AD	0.50 [−0.03,1.03]	0.48 [−0.06,1.02]	0.06 [−0.65,0.76]	0.01 [−0.96, 0.97]	−0.29 [−1.08, 0.50]	0.63 [−0.04, 1.29]	0.68 [0.29, 1.08]**
ND	0.38 [−0.13,0.47]	0.32 [−0.27.0.91]	0.15 [−0.47,0.77]	0.65 [−0.12, 1.41]	−0.22 [−1.01, 0.57]	0.11 [−0.56, 0.77]	0.98 [0.69, 1.27]***

Table showing the severity of externalizing behaviors in off-spring mothers who smoke during pregnancy (versus no MSDP-E) before (Model I) and after controlling for propensity for MSDP-E(Model II), as well as the effect of MSDP-E within each quartile of the MSDP-E risk distribution. Abbreviations: AD - alcohol dependence, ADHD-IN - ADHD inattention, ADHD-HI - ADHD hyperactivity/impulsivity, CD - conduct disorder, ND - nicotine dependence.

Notations:

^ap<.10,

^bN’s vary by group,

^*p<.05,

^**p<.01,

^***p<.001.