Skip to main content
. Author manuscript; available in PMC: 2016 Sep 28.
Published in final edited form as: Nat Med. 2016 Mar 28;22(5):516–523. doi: 10.1038/nm.4068

Figure 5.

Figure 5

Neuroprotection conferred by intestinal dysbiosis requires a reduction in intestinal IL-17+ γδ T cells. (a) Infarct volume in AC Res (n = 6) and AC Sens (n = 8) IL-17 KO mice as measured by Nissl staining of coronal brain sections 3 days after MCAO (bar, 1 mm). (b) Infarct volume of AC Res (n = 7) and AC Sens (n = 9) IL-10 KO mice on day 3 post MCAO. Representative coronal sections with Nissl staining are shown (bar, 1 mm). (c) The graphs represent the percentage of IL-17+ γδ T, TH17 and FoxP3+ cells, respectively, in the LP of the small intestine from AC Res (n = 7) and AC Sens (n = 8) IL-10 KO mice after 2 weeks on antibiotic treatment as measured by flow cytometry. Columns represent mean ± s.e.m.; n.s., not significant (Student’s t-test).