Table 4.

Relationship between specific MGD parameters and dry eye symptoms and signs

	Normal eyelid Vascularity	Abnormal eyelid vascularity†	Normal meibum quality†	Abnormal meibum quality
DEQ5	11.8 (5.2)	11.3 (5.2)	10.5 (5.6)	12.1 (4.7)*
OSDI	34 (22)	35 (26)	32 (25)	36 (26)
Average ocular pain intensity over 1 week recall period (range 0–10)	3.3 (27)	3.4 (2.7)	2.8 (2.7)	3.7 (2.6)*
Itchiness	1.2 (0.9)	1.6 (0.9)	1.2 (1.0)	1.4 (0.9)*
Osmolarity§	307 (18)	300 (17)*	306 (20)	305 (16)
TBUT§	9.8 (4.1)	8.0 (3.1)	10.9 (3.9)	8.6 (3.8)**
Corneal staining§	1.9 (2.4)	2.6 (2.7)	1.5 (2.1)	2.3 (2.3)*
Schirmer’s§	14.2 (7.6)	13.2 (5.9)	15.1 (7.7)	13.2 (6.7)

DEQ5= dry eye questionnaire; OSDI= 0cular surface disease index; TBUT=tear break up time;

^*p value<0.05;

^**p value<0.00005

^†Eyelid vascularity graded on scale of 0 to 3; meibum quality on scale of 0 to 4. For both measures, an abnormal value was defined as a score of 2 or greater in the more severely affected eye.

^§value from more severely affected eye