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Analysis for the strength in the interaction of MDM2 protein after interaction with DHFR protein/MDM2-DHFR complex.
| Parameters for strength in interaction | Before interaction | After interaction |
|---|---|---|
| Free energy of folding (kcal/mol) | −107.23 (MDM2 protein) |
−218.7 (protein complex) |
| DFire (kcal/mol) | −249.79 (MDM2 protein) |
−608.59 (protein complex) |
| Folding rate for MDM2 protein | 1.43209/sec | 2.08699/sec |
| Net area for solvent accessibility for MDM2 protein | 7832.73 Å2 | 5675.83 Å2 |
