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Riociguat dose-normalized area under the plasma concentration–time curve (AUC) at steady state on last day of main study (day 84 of PATENT-1; day 112 of CHEST-1) in patients aged ≤64, 65–74, and ≥75 years (left) and in men and women (right). Data show box-and-whisker plots with fifth, 25th, 50th, 75th, and 95th percentiles.
