Table 2.
Baseline demographic characteristics of healthy individuals (normal renal function) and patients with mild, moderate, or severe renal impairment in the mixed population of smokers and nonsmokers
| Demographic characteristic | Normal (CLCR > 80 mL/min) |
Mild (CLCR = 50–80 mL/min) |
Moderate (CLCR = 30–49 mL/min) |
Severe (CLCR < 30 mL/min) |
Total |
|---|---|---|---|---|---|
| Patients | 16 | 15 | 16 | 16 | 63 |
| Age, mean (range), years | 60.3 (44.0–69.0) | 63.9 (53.0–74.0) | 60.1 (36.0–78.0) | 61.2 (39.0–75.0) | 61.3 (36.0–78.0) |
| Female | 5 (31) | 8 (53) | 6 (38) | 4 (25) | 23 (37) |
| White | 16 (100) | 15 (100) | 16 (100) | 16 (100) | 63 (100) |
| BMI, mean (SD) | 27.5 (2.7) | 27.3 (4.1) | 28.3 (3.6) | 26.1 (3.4) | 27.3 (3.5) |
| Current smoker | 2 (13) | 3 (20) | 4 (25) | 2 (13) | 11 (17) |
Note
Except where indicated, data are no. (%) of individuals. Means are arithmetic means. BMI: body mass index; CLCR, creatinine clearance.