Table 1.
Demographics and baseline hemodynamics of the two cohorts studied
| CTEPH cohort (N = 18) | Control cohort (N = 15) | P valuea | |
|---|---|---|---|
| Demographics | |||
| Age, years | 51.0 (44.0–64.0) | 46 (42.0–61.0) | 0.77 |
| Female sex, no. | 7 | 10 | 0.17 |
| Resting hemodynamics | |||
| Mean PA pressure, mmHg | 52.0 (38.0–66.0) | 15.0 (12.0–18.0) | <0.001 |
| Wedge pressure, mmHg | 11.0 (10.0–12.0) | 8.0 (7.0–12.0) | 0.17 |
| Cardiac index | 1.98 (1.66–2.68) | 2.95 (2.63–3.4) | <0.001 |
| PVR, Wood units | 10.6 (0.66–17.3) | 1.01 (0.85–1.64) | <0.001 |
| RA pressure, mmHg | 14.0 (11.0–16.0) | 5.0 (3.0–8.0) | <0.001 |
| Stroke volume, mL | 50.0 (32.9–77.9) | 79.3 (65.8–92.5) | 0.02 |
| Compliance | 0.84 (0.61–1.56) | 5.7 (4.64–7.53) | <0.001 |
Note
Data are reported as median (interquartile range) unless otherwise specified. CTEPH: chronic thromboembolic pulmonary hypertension; PA; pulmonary arterial; PVR: pulmonary vascular resistance; RA: right atrial.
a
P values were computed on the basis of a Wilcoxon 2-sample exact test with a 2-sided P value, with the exception of gender proportions, which were compared using the Fisher exact test.