Table S2.

Lobar measures of arterial and venous vessel volume distribution

	CTEPH	Control	P valuea
Arterial fractions
Small vessels, BV5ART/TBVART
Right lung, upper lobe	0.51 (0.44–0.55)	0.66 (0.59–0.74)	0.0005
Right lung, middle lobe	0.54 (0.47–0.59)	0.66 (0.62–0.72)	0.002
Right lung, lower lobe	0.45 (0.27–0.53)	0.59 (0.46–0.66)	0.016
Left lung, upper lobe	0.43 (0.35–0.48)	0.58 (0.51–0.72)	0.0003
Left lung, lower lobe	0.36 (0.30–0.44)	0.56 (0.44–0.61)	0.0009
Large vessels, BV>10ART/TBVART
Right lung, upper lobe	0.31 (0.26–0.37)	0.19 (0.14–0.23)	<0.0001
Right lung, middle lobe	0.28 (0.21–0.35)	0.18 (0.14–0.23)	0.005
Right lung, lower lobe	0.33 (0.30–0.47)	0.26 (0.21–0.33)	0.04
Left lung, upper lobe	0.34 (0.29–0.39)	0.22 (0.16–0.28)	0.0002
Left lung, lower lobe	0.37 (0.33–0.46)	0.27 (0.23–0.35)	0.005
Venous fractions
Small vessels, BV5VEIN/TBVVEIN
Right lung, upper lobe	0.53 (0.46–0.59)	0.56 (0.54–0.60)	0.15
Right lung, middle lobe	0.51 (0.43–0.53)	0.57 (0.52–0.61)	0.02
Right lung, lower lobe	0.44 (0.35–0.52)	0.51 (0.43–0.59)	0.13
Left lung, upper lobe	0.47 (0.36–0.52)	0.54 (0.49–0.57)	0.02
Left lung, lower lobe	0.39 (0.31–0.46)	0.49 (0.38–0.56)	0.03
Large vessels, BV>10VEIN/TBVVEIN
Right lung, upper lobe	0.25 (0.23–0.29)	0.24 (0.23–0.28)	0.56
Right lung, middle lobe	0.27 (0.22–0.29)	0.23 (0.18–0.30)	0.71
Right lung, lower lobe	0.31 (0.26–0.37)	0.32 (0.28–0.35)	0.58
Left lung, upper lobe	0.25 (0.21–0.30)	0.27 (0.25–0.29)	0.82
Left lung, lower lobe	0.31 (0.29–0.35)	0.33 (0.25–0.37)	0.82
Arterial/venous ratios
Small vessels, BV5ART/BV5VEIN
Right lung, upper lobe	1.24 (0.96–1.39)	1.15 (1.1–1.36)	0.96
Right lung, middle lobe	1.41 (0.92–1.88)	1.39 (1.18–1.62)	1.0
Right lung, lower lobe	1.20 (0.96–1.46)	1.21 (1.03–1.37)	0.87
Left lung, upper lobe	1.30 (1.14–1.51)	1.27 (1.12–1.36)	0.38
Left lung, lower lobe	1.28 (1.03–1.43)	1.20 (1.05–1.29)	0.20
Large vessels, BV>10ART/BV>10VEIN
Right lung, upper lobe	1.59 (1.25–2.09)	0.79 (0.58–1.15)	<0.0001
Right lung, middle lobe	1.5 (0.8–2.40)	0.88 (0.58–1.49)	0.12
Right lung, lower lobe	1.41 (1.02–2.3)	0.88 (0.77–1.2)	0.01
Left lung, upper lobe	1.8 (1.49–2.88)	1.0 (0.68–1.33)	<0.0001
Left lung, lower lobe	1.87 (1.28–2.42)	0.97 (0.8–1.42)	0.0005
Overall, TBVART/TBVVEIN
Right lung, upper lobe	1.26 (1.1–1.53)	1.05 (0.96–1.19)	.02
Right lung, middle lobe	1.53 (0.96–1.66)	1.16 (1.01–1.34)	0.32
Right lung, lower lobe	1.30 (0.96–1.84)	1.10 (0.98–1.19)	0.19
Left lung, upper lobe	1.43 (1.26–1.68)	1.12 (0.99–1.24)	0.002
Left lung, lower lobe	1.47 (1.24–1.78)	1.08 (0.93–1.17)	0.001

^NoteData are reported as median (interquartile range). ART: arterial; BV5: blood vessel volume for vessels with a cross-sectional area ≤ 5 mm²; BV>10: blood vessel volume for vessels with a cross-sectional area > 10 mm²; TBV: total blood vessel volume; VEIN: venous.

^aP value based on a Wilcoxon exact test with a 2-sided P value.