Table 7. The 17 SNVs significantly different between case and control.
Gene | Chr | Pos | Ref | Obs | caseRef | caseAlt | controlRef | controlAlt | FisherExactTestPvalue | Sanger sequencing validated |
---|---|---|---|---|---|---|---|---|---|---|
PPARG | chr3 | 12475632 | G | A | 15 | 1 | 1600 | 0 | 0.00990099 | No |
CPT2 | chr1 | 53679028 | G | A | 15 | 1 | 1599 | 1 | 0.019710021 | Yes |
FCGR2A | chr1 | 161479745 | A | G | 13 | 3 | 836 | 764 | 0.023221855 | Yes |
RPAIN | chr17 | 5326145 | C | G | 2 | 14 | 638 | 962 | 0.036500478 | Yes |
TLR3 | chr4 | 187004074 | C | T | 6 | 10 | 1069 | 531 | 0.028998842 | Yes |
NOS3 | chr7 | 150704250 | C | G | 12 | 4 | 785 | 815 | 0.04531093 | Yes |
ABCB1 | chr7 | 87179601 | A | G | 13 | 3 | 862 | 738 | 0.040826503 | Yes |
LEP | chr7 | 127892124 | A | G | 15 | 1 | 1597 | 3 | 0.039055387 | Yes |
TLR4 | chr9 | 120470894 | C | G | 15 | 1 | 1600 | 0 | 0.00990099 | Yes |
KLRC2 | chr12 | 10587111 | A | G | 3 | 13 | 923 | 677 | 0.003533467 | Yes |
chr12 | 10588530 | C | G | 14 | 2 | 835 | 765 | 0.004729536 | Yes | |
CES1 | chr16 | 55844509 | T | C | 15 | 1 | 1600 | 0 | 0.00990099 | Yes |
DNMT1 | chr19 | 10265312 | T | C | 0 | 16 | 433 | 1167 | 0.00938611 | Yes |
chr19 | 10265333 | A | G | 15 | 1 | 1600 | 0 | 0.00990099 | Yes | |
chr19 | 10265372 | C | T | 15 | 1 | 1600 | 0 | 0.00990099 | Yes | |
MX1 | chr21 | 42817930 | G | A | 15 | 1 | 885 | 715 | 0.001564732 | Yes |
chr21 | 42824661 | A | G | 12 | 4 | 766 | 834 | 0.042066821 | Yes |