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. 2016 May 9;6:25722. doi: 10.1038/srep25722

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Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Kaplan-Meier analysis and log-rank test of Notch2 for OS. High Notch2 protein expression significantly predicted decreased OS. (B) Kaplan-Meier analysis and log-rank test of Notch2 for PFS. High Notch2 protein expression was significantly associated with decreased PFS. ROC curve for Notch2 according to OS (C) and PFS (D) predictions. The AUC value was 0.63 ± 0.06 (P = 0.044) according to the OS prediction and 0.61 ± 0.54 (P = 0.044) according to the PFS prediction. Abbreviations: OS: overall survival; PFS: progression-free survival.