Table 3.
Predictive logistic regression of adherence to medication treatment at six months.
| Independent variables | Odds Ratio (OR) for worse non-adherencea | 95% Confidence interval | Chi-square (n = 1501, df = 1) | p-Valuesb |
|---|---|---|---|---|
| Alcohol/drugs at baselinec | 1.759 | 1.399-2.212 | 23.36 | <0.0001 |
| Insight at baseline | 1.122 | 1.035-1.217 | 7.80 | 0.0052 |
| Hostility at baseline | 1.122 | 1.017-1.238 | 5.26 | 0.0218 |
| Akathisia at baseline | 1.043 | 0.802-1.357 | 0.10 | n.s. |
| Parkinsonism at baseline | 0.740 | 0.577-0.949 | 5.65 | 0.0175 |
| Dyskinesia at baseline | 0.749 | 0.549-1.023 | 3.31 | n.s. |
| Positive symptoms at baselined | 1.009 | 0.987-1.032 | 0.61 | n.s. |
| Study (CATIE vs. EUFEST) | 1.628 | 1.200-2.209 | 9.80 | 0.0017 |
| Age | 0.989 | 0.978-1.000 | 3.95 | 0.0468 |
| Male gender | 1.219 | 0.958-1.550 | 2.60 | n.s. |
OR>1 and OR<1, respectively, indicate increased or decreased non-adherence.
p-Values in bold remain significant after Hochberg's correction for multiple testing.
Any use, combined.
PANSS positive symptoms excluding hostility.