Figure 1. Function classification of the differentially expressed proteins between ETEC-induced diarrheal piglets and controls.

ETEC-induced diarrhea in piglets were established by orally inoculation of ETEC W25K for five consecutive days at dosage of 10¹⁰ CFUs per day. As a control, piglets were orally infected with the same volume of LB medium. The differentially expressed proteins between 6 diarrheal piglets after ETEC infection and 6 control piglets were characterized by iTRAQ-based proteomics, and then the functional annotations of 378 differentially expressed proteins were conducted using the gene ontology (GO) annotation software. iTRAQ: isobaric tags for relative and absolute quantitation; ETEC: Enterotoxigenic Escherichia coli.