Table 1. Statistically significant clusters (FDC1) from WIFA-Seq for 37 patients with GBM.
Chr | Start | End | Score | # of patients | P-values | Genes |
---|---|---|---|---|---|---|
7 | 53982101 | 56449401 | 504208.00 | 25 | 0.00 | EGFR |
9 | 19626001 | 29431601 | −156930.60 | 26 | 0.00 | CDKN2A|CDKN2B |
12 | 56919201 | 59971201 | 119463.40 | 11 | 0.00 | CDK4 |
1 | 203277901 | 205825501 | 110989.60 | 7 | 0.01 | MDM4 |
4 | 52663201 | 56488401 | 97355.73 | 7 | 0.00 | PDGFRA |
12 | 69038101 | 69416901 | 52436.32 | 6 | 0.01 | MDM2 |
6 | 106784301 | 108840801 | 49466.33 | 4 | 0.04 | |
10 | 88984001 | 90359501 | −13045.48 | 14 | 0.06 | PTEN |
18 | 25736501 | 27397901 | −10002.23 | 9 | 0.01 | |
19 | 34288701 | 39415601 | 9068.60 | 7 | 0.00 | |
12 | 16587901 | 21884101 | −8619.56 | 8 | 0.07 | |
6 | 162272701 | 164169001 | −7932.19 | 3 | 0.03 | PARK2|QKI |
2 | 233933901 | 235859501 | −7083.54 | 2 | 0.00 | |
15 | 35156501 | 37062401 | −6761.21 | 14 | 0.06 | |
11 | 66176001 | 67434201 | 6164.80 | 2 | 0.01 | |
16 | 4027401 | 5129501 | 6045.22 | 2 | 0.02 | |
16 | 84363801 | 85714601 | 5984.56 | 4 | 0.02 | |
14 | 33407901 | 35914401 | −5872.19 | 3 | 0.04 | NPAS3* |
21 | 9411001 | 11188101 | −5284.48 | 23 | 0.00 | |
7 | 153749801 | 156394701 | −4123.94 | 5 | 0.02 | |
8 | 1902201 | 2776501 | −3727.91 | 3 | 0.01 | |
4 | 49095601 | 49660001 | −3547.28 | 4 | 0.02 | |
20 | 58229601 | 58514701 | −2890.01 | 16 | 0.00 | |
20 | 3684901 | 4517301 | 2882.16 | 2 | 0.04 | |
8 | 43027601 | 43838801 | 1316.54 | 2 | 0.01 |
Clusters are ordered by cluster scores. Among the genes in the clusters, some genes related to GBM are specified. Previously known GBM genes in the silver standard are shown without asterisks.